Purpose: To study the variation of iris thicknesses in different regions and explore the possible correlations with age and gender.
Methods: Healthy Chinese adults were recruited; the anterior segment of their eyes was imaged by swept-source optical coherence tomography (SS-OCT). The horizontal scan of the right eye was selected, and the thicknesses of both the nasal and temporal irises were measured at 199 evenly spaced points.
Results: A total of 233 subjects with an average age of 36.79±10.04 years (range 19 to 62) were included in the final analysis. The mean iris thicknesses of the temporal and nasal sides were 364.79±47.58 μm and 372.44±43.75 μm, respectively. The mean nasal iris thickness was positively correlated with age (β=0.9 μm/year, P=0.002), but the temporal one was not (β=0.077 μm/year, P=0.806). At 139 points of the nasal and 146 of the temporal, the iris thickness was significantly correlated with age (P＜0.05). The thicknesses of the peripheral and pupillary part were positively correlated with age, while the middle part was negatively correlated with age. No significant difference was observed in the mean iris thickness between genders (temporal: t=1.597, p=0.112; nasal: t=1.870, p=0.063), but females had a thicker iris than males at 50 points in the temporal side and 49 in the nasal side (P＜0.05); no point in males was observed to have thicker iris than in females.
Conclusion: Using SS-OCT and novel method, thicknesses of the iris at different regions were measured. The thicknesses of the peripheral and pupillary irises increase with age, while the thicknesses of the middle part decrease.
Iris, Anterior chamber, Glaucoma, Anatomy, Age
Under processing in revision
Received date: September 23, 2019
©2020 Chunhui Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Chunhui Jiang (2020) Variation of Iris Thickness in Different Regions in Healthy Chinese Adults: An Optical Coherence Tomography Study. OSP Journal of Ophthalmolog. 1: JOO-1-104
Department of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, No.83 Fenyang Road, Shanghai 200031, People’s Republic of China. firstname.lastname@example.org;
Department of Ophthalmology, People’s Hospital of Shanghai, No. 5,
Shanghai 200240, People’s Republic of China. email@example.com